NMR spectroscopy is a powerful analytical technique used to determine the three-dimensional structure, dynamics, and interactions of molecules at atomic resolution. In drug discovery, it plays a critical role in several key areas:

Structure Elucidation: NMR is used to confirm the chemical structure and stereochemistry of small-molecule drug candidates, especially during hit validation and lead optimization.

Conformational Analysis: For both small molecules and biologics, NMR provides insights into molecular flexibility, folding, and stability, aiding in formulation and developability assessments.